Professor Stephen Holgate CBE

Professor Stephen T Holgate CBE
Clinical Professor of Immunopharmacology


  • Board member of the Prince of Wales Foundation of Integrated Health.
  • Joint Founder of Southampton’s full-time Specialist Asthma & Allergy Clinics (one of only six in the country).
  • Founder of The AAIR Charity and AAIR Chairman of Trustees.
  • Appointed to Medical Research Council Clinical Chair in 1987.
  • Chair of the DEFRA (Department of The Environment for Food & Rural Affairs) Expert Panel on Air Quality Standards.
  • Member of the Department of Health Committee on the Medical Effects of Air Pollution (previously founding chair for 10 years).
  • Member of the Royal Commission on Environmental Pollution.
  • Chair of the Science Council’s Science in Health Group
  • Chair of the National Allergy Strategy Group
  • Author of over 700 peer reviewed papers and scientific contributions to journals and editor of major textbooks on asthma and rhinitis
  • Chair of the Medical research Council’s Subcommittee on Evaluation

Asthma, Allergies, Air Pollution, Virus Infections (lung), Genetics.

Professor Stephen Holgate TrusteeAsthma and allergy are clearly associated but are not synonymous with each other. We have discovered that a wide range of environmental factors can play a key part in the cause and worsening of asthma. An important area of Professor Holgate’s research is to understand how influential these environmental factors are and, in the case of air pollution, to advise the Government accordingly. These factors include:
Air pollutants e.g: ozone, particles
Allergens such as: house dust mite allergens
Viruses e.g: the common cold viruses
Another important component of asthma is hereditability. During the past decade Professor Holgate headed the research, which led to the discovery of ADAM33 – number one of a number of asthma genes. A major focus of his work now is to understand how this gene affects the causes and worsening of asthma.

Professor Holgate is one of the top specialists in his field, both nationally and internationally. His many leading appointments, including that of Government advisor, underline his level of expertise. He is regularly interviewed by the local and national press regarding most aspects of asthma and allergies.

* Immunopharmacology is the study of the affects of drugs on the immune system.

Contact: RCMB, mailpoint 810, Level D, Centre Block, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD.

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